If you’ve ever used a skincare product with a rich, dreamy blue color, chances are you’ve already met Guaiazulene—even if you didn’t realize it at the time.
This under-the-radar ingredient doesn’t get as much spotlight as retinol or niacinamide, but it should, especially if you work with sensitive or post-treatment skin.
Guaiazulene (gwai-uh-zoo-leen) is a naturally derived compound that comes from chamomile oil or guaiac wood. It’s part of the azulene family—yep, the same one that gives blue tansy its color.
Guaiazulene is known for its anti-inflammatory, skin-soothing, and barrier-repairing properties, and here’s why we think this ingredient deserves more love in the treatment room and on your retail shelves:
1. It calms irritated skin. Fast.
Whether you’re doing extractions, peels, or any kind of advanced treatment, Guaiazulene can help reduce redness and calm that post-treatment heat. It’s especially helpful when you're working with reactive or compromised skin.
2. It plays well with actives.
Some calming ingredients are great in theory but don’t always work well alongside acids or retinoids. Not the case here. Guaiazulene can hang. It helps buffer irritation without muting the results of stronger ingredients.
3. It’s perfect for barrier repair.
We talk a lot about barrier function these days—and for good reason. Guaiazulene helps support the skin’s recovery process, which makes it ideal for post-treatment protocols or retail kits for clients dealing with barrier damage.
Now that you know what Guaiazulene is and why it’s a game-changer for calming and restoring skin—let us introduce you to Corthe's Dermo Sensitive Relief Ampoule.
This highly advanced calming ampoule is designed exclusively for backbar use and formulated with a powerhouse blend of anti-inflammatory, hydrating, and skin-repairing ingredients.
Guaiazulene – Our blog star! This azulene derivative helps reduce redness, calm inflammation, and support recovery.
Centella Asiatica Extract – A staple in K-beauty for a reason—promotes healing, collagen production, and soothes irritation.
Hyaluronic Acid + Polyglutamic Acid – A one-two punch of deep hydration and barrier support. Polyglutamic acid enhances moisture retention while hyaluronic acid plumps and hydrates.
Allantoin + Glycine Soja (Soybean) Germ Extract – Deliver lasting soothing effects for overstimulated or sensitive skin.
Together, these ingredients form a multifaceted approach to calming, replenishing, and fortifying the skin barrier—making this ampoule ideal after advanced treatments, or anything that may cause erythema or barrier disruption.
INCI (for the ingredient lovers):Water, Glycerin, Butylene Glycol, Cyclopentasiloxane, 1,2-Hexanediol, Cyclohexasiloxane, Phenyl Trimethicone, Dimethiconol, PEG-5 Glyceryl Isostearate, PEG-8 Glyceryl Isostearate, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, PEG-20 Glyceryl Isostearate, Panthenol, PEG-40 Hydrogenated Castor Oil, Sodium Polyacrylate, Disodium EDTA, Allantoin, Dimethicone, Glycine Soja (Soybean) Germ Extract, Hyaluronic Acid, Centella Asiatica Extract, Trideceth-6, Propylene Glycol, Polyglutamic Acid, PEG/PPG-18/18 Dimethicone, Chamomilla Recutita (Matricaria) Flower Extract, Guaiazulene
